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Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
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PACEMweb: a tool for aggregate consumer exposure assessment.

Christiaan J E Delmaar1, Roel Schreurs2, Martine I Bakker2

  • 1National Institute for Public Health and the Environment-RIVM, Bilthoven, The Netherlands. christiaan.delmaar@rivm.nl.

Journal of Exposure Science & Environmental Epidemiology
|December 15, 2022
PubMed
Summary
This summary is machine-generated.

Assessing aggregate chemical exposure from consumer products is vital for safety. The Probabilistic Aggregate Consumer Exposure Model (PACEM) and its web tool, PACEMweb, offer a new, realistic approach to this assessment.

Keywords:
Aggregate ExposureChemicalsConsumer productsExposure modellingPACEM

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Area of Science:

  • Environmental Health
  • Risk Assessment
  • Consumer Product Safety

Background:

  • Chemical safety relies on understanding aggregate human exposure from diverse consumer products.
  • Assessing combined exposure from multiple products is crucial for accurate risk evaluation.

Purpose of the Study:

  • Introduce the Probabilistic Aggregate Consumer Exposure Model (PACEM) and its web-based tool, PACEMweb.
  • Provide a publicly available platform for realistic aggregate consumer exposure assessment.

Main Methods:

  • Utilize a person-oriented simulation approach with realistic product usage data from European surveys.
  • Incorporate individual use, co-use patterns, and product composition variability.
  • Include data on personal care products (PCPs) and household cleaning products (HCPs).

Main Results:

  • PACEM has been implemented in the user-friendly PACEMweb tool.
  • The model's person-oriented method has been validated through various applications and biomonitoring comparisons.
  • PACEM assessments provide insights into exposure distribution and key contributing products.

Conclusions:

  • PACEM facilitates realistic aggregate exposure assessment for chemicals in consumer products.
  • PACEMweb enhances informed decision-making in chemical risk management.
  • This tool is the first of its kind for public use in aggregate exposure assessment.