Related Experiment Video
Updated: Aug 17, 2025
Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Pertussis in India: Past, Present, and Future.
A J Chitkara1, S Balasubramanian2, Jaydeep Choudhury3
1Department of Pediatrics, Max Super Specialty Hospital, Shalimar Bagh, 118, Vaishali, Pitampura, Delhi, 110088, India. drajchitkara@outlook.com.
Pertussis, or whooping cough, is resurging globally. In India, underestimation of pertussis cases and inconsistent vaccine coverage hinder control efforts, necessitating improved surveillance and vaccination strategies.
Area of Science:
- Immunology
- Epidemiology
- Public Health
Background:
- Pertussis (whooping cough) incidence has decreased due to vaccines but is resurging globally.
- India, despite a successful infant immunization program, faces challenges in pertussis control, with underreporting and inconsistent vaccine coverage.
- Renewed interest in pertussis in India is driven by global trends and concerns for neonatal cases.
Purpose of the Study:
- To understand pertussis epidemiology and disease burden in India.
- To explore opportunities for improving pertussis prevention and control in India.
- To address challenges in pertussis surveillance and vaccination strategies.
Main Methods:
- Virtual Global Pertussis Initiative (GPI) Annual Meeting in October 2020.
- Consensus discussion on underestimation of pertussis cases due to passive surveillance and diagnostic difficulties.
- Review of India's vaccine landscape, including whole-cell pertussis (wP) and acellular pertussis (aP) vaccines, and coverage inconsistencies.
Main Results:
- Pertussis cases are significantly underestimated in India.
- Inconsistent vaccine coverage is linked to availability, healthcare access, and administrative issues.
- Active surveillance and serosurveillance among reproductive-age women are recommended.
Conclusions:
- Active surveillance is optimal for pertussis in India.
- Serosurveillance can inform policy changes for rational vaccine use (wP and aP).
- Increased vaccination coverage across multiple age groups and engagement with NGOs for antenatal immunization are crucial for pertussis control.
More Related Videos
10:04Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
09:33Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
Published on: December 23, 2022
Related Concept Videos
01:28Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:29Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
01:28Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
01:51Vaccinations
01:25Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
01:26Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...