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A 5-day regimen of cyclophosphamide, adriamycin, platinum (CAP) in refractory breast cancer
A Fornasiero1, O Daniele, S M Aversa
1Department of Medical Oncology, Padua General Hospital, Italy.
Chemioterapia : International Journal of the Mediterranean Society of Chemotherapy
|August 1, 1987
Abstract:
The activity of the association of cis-platinum with Adriamycin and cyclophosphamide (CAP), as "rescue" chemotherapy for the treatment of refractory and relapsing advanced breast cancer, is presented. Of 42 evaluable patients, previously treated with chemotherapy +/- hormone therapy, 4 (9.5%) achieved a complete response, 15 (35%) had a partial response (CR + PR = 45%). Major toxicity observed was: nausea and vomiting in 95% of patients and leukopenia in 60%.