Isotretinoin, Vitamin A Supplements, and Unintended Pregnancies in Post Roe v. Wade America
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Updated: Aug 17, 2025

Isolation of Lung Retinoid-Containing Cells by Cell Sorting
Published on: April 11, 2025
Praneet S Paidisetty1, Leonard K Wang2, Dina H Zamil3
1Dermatology, McGovern Medical School, The University of Texas Health Science Center, Houston, USA.
Abstract:
Isotretinoin is a potent vitamin A derivative that is used to treat acne. However, despite its utility in dermatologic care, it is also highly teratogenic and can cause severe life-threatening fetal abnormalities in the first trimester of pregnancy. As a result, existing regulations are stringent in order to prevent accidental pregnancies in women taking isotretinoin. In the unlikely case of an unintended pregnancy, while taking isotretinoin, a woman could terminate her pregnancy with an abortion. However, with the recent overturning of Roe v. Wade, we explore the consequences of this landmark United States Supreme Court ruling with special attention to those taking isotretinoin and over-the-counter (OTC) vitamin A supplements.
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