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Updated: Aug 17, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Impact of COVID-19 on Pregnancy and Maternal-Neonatal Outcomes: A Narrative Review

Sweta Sahu1, Guddi Laishram1, Asmita Rannaware1

  • 1Community Medicine, School of Epidemiology and Public Health, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Cureus
|December 16, 2022
PubMed

Insights

The COVID-19 pandemic posed risks to pregnant women, increasing susceptibility to complications. While most infections were mild, some cases resulted in miscarriage and fetal growth issues.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Public Health

Background:

  • The COVID-19 pandemic created a global health crisis, impacting various populations.
  • Pregnant women, the elderly, and individuals with comorbidities faced heightened risks.
  • Emerging evidence suggests COVID-19 affects multiple organ systems, including the placenta.

Purpose of the Study:

  • To review existing literature on pregnancies affected by COVID-19.
  • To analyze the pandemic's effects on maternal, perinatal, and neonatal outcomes.

Main Methods:

  • Literature search conducted using Google Scholar and PubMed (Medline).
  • Data synthesis included clinical manifestations, fetal outcomes, vertical transmission, and pregnancy impacts.

Main Results:

  • Most pregnant women with COVID-19 experienced mild or asymptomatic infections.
  • The impact on the fetus was generally insignificant.
  • However, some cases reported miscarriage and fetal growth retardation.

Conclusions:

  • Pregnant women require special attention during the COVID-19 pandemic.
  • While generally mild, COVID-19 can lead to severe maternal and fetal complications in some instances.
  • Further research is needed to fully understand long-term impacts.

Keywords:
covid-19gestationmaternal healthmaternal-fetal transmissionmiscarriagepregnancysars-cov-2vertical transmission

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