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Published on: January 20, 2019
Development of clinical pathways to improve multidisciplinary care of high-risk pediatric oncology patients
Agnes Reschke1,2, Rebecca M Richards1,3, Stephanie M Smith1
1Division of Hematology, Oncology, Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, United States.
Insights
Clinical pathways improve care for pediatric oncology patients with emergencies like hyperleukocytosis or anterior mediastinal mass. These evidence-based tools standardize management, aiming to reduce complications and improve outcomes.
Area of Science:
- Pediatric Oncology
- Clinical Medicine
- Evidence-Based Practice
Background:
- Clinical pathways are effective in pediatric hospital medicine but underutilized in pediatric oncology.
- Pediatric oncology patients often present with oncologic emergencies requiring urgent, multidisciplinary care.
- Few studies document clinical pathways for high-risk pediatric oncology populations.
Purpose of the Study:
- To present two novel clinical pathways for pediatric oncology patients presenting with hyperleukocytosis or anterior mediastinal mass.
- To provide a framework for immediate, multidisciplinary care of these high-risk patients.
- To facilitate collaboration, expedite diagnosis, and streamline treatment initiation.
Main Methods:
- Development of two clinical pathways using a multidisciplinary approach at a single institution.
- Focus on patients with hyperleukocytosis or anterior mediastinal mass.
- Application in initial management, often within the pediatric intensive care unit.
Main Results:
- Established critical frameworks for immediate care of high-risk pediatric oncology patients.
- Facilitated multidisciplinary collaboration and timely treatment initiation.
- Aimed to standardize care for improved patient outcomes.
Conclusions:
- Clinical pathways offer a standardized approach to managing oncologic emergencies in pediatric oncology.
- Implementation can decrease morbidity and mortality in high-risk pediatric cancer patients.
- Standardized care pathways hold potential for excellent patient outcomes.
Abstract:
Clinical pathways are evidence-based tools that have been integrated into many aspects of pediatric hospital medicine and have proven effective at reducing in-hospital complications from a variety of diseases. Adaptation of similar tools for specific, high-risk patient populations in pediatric oncology has been slower, in part due to patient complexities and variations in management strategies. There are few published studies of clinical pathways for pediatric oncology patients. Pediatric patients with a new diagnosis of leukemia or lymphoma often present with one or more "oncologic emergencies" that require urgent intervention and deliberate multidisciplinary care to prevent significant consequences. Here, we present two clinical pathways that have recently been developed using a multidisciplinary approach at a single institution, intended for the care of patients who present with hyperleukocytosis or an anterior mediastinal mass. These clinical care pathways have provided a critical framework for the immediate care of these patients who are often admitted to the pediatric intensive care unit for initial management. The goal of the pathways is to facilitate multidisciplinary collaborations, expedite diagnosis, and streamline timely treatment initiation. Standardizing the care of high-risk pediatric oncology patients will ultimately decrease morbidity and mortality associated with these diseases to increase the potential for excellent outcomes.
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