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Convenient exosome separation by phosphatidylserine targeting polymer brush materials
Shuming Li1, Shasha Hao1, Yetong Yang1
1Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry & Chemical Engineering, Shaanxi Normal University, Xi'an, 710119, P. R. China. zhangjing8902@snnu.edu.cn.
Abstract:
We report phosphatidylserine targeting polymer brush materials to selectively separate exosomes. This method provides an efficient separation strategy with ordinary centrifuge force, which improves the integrity and purity of the exosomes. Compared with the common methods, the content of contaminated lipoprotein in the resulting exosomes decreased obviously.
