Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thermal Conductivity Reduction in Heterostructure Multilayer Composites by Phonon Density of State Mismatch.

ACS applied materials & interfaces·2026
Same author

Moisture-Gated Bio-Semiconductor Electronic Tattoos for Continuous and Imperceptible On-Skin Respiratory Monitoring.

ACS sensors·2026
Same author

Computational Mechanics Model to Evaluate the Structural Maintenance of Catenated Hydrogen-Bonded Organic Frameworks.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Highly Tough, Notch-Insensitive, and Fast Self-Healing Thermoplastic Polyurethane Elastomers by Tailored Soft Segment Design.

Angewandte Chemie (International ed. in English)·2026
Same author

All-Atomic Computational Perspectives for Understanding Morphable Electric Double Layers: A Review.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

µm-Thick and Water-Taping Protein Electronic Tattoos for Multifunctional On-Skin Electronics.

Small (Weinheim an der Bergstrasse, Germany)·2025

Related Experiment Video

Updated: Aug 17, 2025

Reactive Inkjet Printing and Propulsion Analysis of Silk-based Self-propelled Micro-stirrers
09:23

Reactive Inkjet Printing and Propulsion Analysis of Silk-based Self-propelled Micro-stirrers

Published on: April 26, 2019

7.9K

Engineering Silk Protein to Modulate Polymorphic Transitions for Green Lithography Resists.

Soon-Chun Chung1, Joon-Song Park1, Rakesh Kumar Jha2

  • 1Material Research Center, Samsung Advanced Institute of Technology, Samsung Electronics Co., Ltd., Suwon 16678, Korea.

ACS Applied Materials & Interfaces
|December 16, 2022
PubMed
Summary

Synthetically engineered silk protein enables on-demand functions for biomedical devices. This research details creating a high-performance, green lithography photoresist from silk, paving the way for industrial scale production.

Keywords:
green photoresistlithographypolymorphic transitionsilk proteinsynthetic biology

More Related Videos

Silk Film Culture System for in vitro Analysis and Biomaterial Design
11:19

Silk Film Culture System for in vitro Analysis and Biomaterial Design

Published on: April 24, 2012

19.5K
In Vivo Targeted Expression of Optogenetic Proteins Using Silk/AAV Films
06:11

In Vivo Targeted Expression of Optogenetic Proteins Using Silk/AAV Films

Published on: February 26, 2019

8.6K

Related Experiment Videos

Last Updated: Aug 17, 2025

Reactive Inkjet Printing and Propulsion Analysis of Silk-based Self-propelled Micro-stirrers
09:23

Reactive Inkjet Printing and Propulsion Analysis of Silk-based Self-propelled Micro-stirrers

Published on: April 26, 2019

7.9K
Silk Film Culture System for in vitro Analysis and Biomaterial Design
11:19

Silk Film Culture System for in vitro Analysis and Biomaterial Design

Published on: April 24, 2012

19.5K
In Vivo Targeted Expression of Optogenetic Proteins Using Silk/AAV Films
06:11

In Vivo Targeted Expression of Optogenetic Proteins Using Silk/AAV Films

Published on: February 26, 2019

8.6K

Area of Science:

  • Biomaterials Science
  • Materials Chemistry
  • Nanotechnology

Background:

  • Silk protein shows promise for biomedical devices, but lacks functional tunability.
  • Modifying natural silk protein for specific applications is challenging.

Purpose of the Study:

  • To investigate structure-property relationships in synthesized silk protein.
  • To develop a green-lithographic, high-performance protein resist using engineered silk.
  • To explore silk-based resists for both deep-UV and electron-beam lithography.

Main Methods:

  • Artificially synthesized silk protein with controlled building block ratios.
  • 193 nm laser irradiation to induce polymorphic transitions (β-sheet to α-helix).
  • Characterization of molecular structure, crystallization, and tyrosine content.

Main Results:

  • Building block composition dictates β-sheet crystallite size and content.
  • Tyrosine cleavage by laser irradiation triggers structural transitions.
  • Engineered silk exhibits high crystallization and tyrosine-richness, suitable for photoresists.
  • Demonstrated water-based synthesis and lithography for green processing.
  • Fabricated nanopatterned color filters with reduced angle dependence.

Conclusions:

  • Tailoring synthesized silk protein's molecular structure enables on-demand functions.
  • Developed a high-performance, environmentally friendly protein resist for advanced lithography.
  • Findings support industrial-scale production of functionalized silk proteins for diverse applications.