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Lung Transplantation for COVID-19 Pulmonary Sequelae
Hiromu Kehara1, Chirantan Mangukia1, Gengo Sunagawa1
1Division of Cardiovascular Surgery, Temple University and Lewis Katz School of Medicine, Philadelphia, PA.
Transplantation
|December 16, 2022
Summary
Lung transplantation offers favorable early outcomes for severe COVID-19 lung failure, even in complex patients. This procedure is a vital option for managing persistent pulmonary sequelae of the virus.
Area of Science:
- Pulmonology
- Transplant Surgery
- Infectious Diseases
Background:
- The role of lung transplantation for coronavirus disease 2019 (COVID-19)-related lung failure is evolving.
- 20 patients underwent lung transplantation for COVID-19 lung failure between January 2021 and April 2022.
Approach:
- Clinical and intraoperative characteristics and early outcomes of 20 lung transplant recipients for COVID-19 lung failure were reviewed.
- Data included patient demographics, comorbidities, transplant type, and postoperative complications.
Key Points:
- 55% of patients had pre-existing chronic lung disease.
- 15% required extracorporeal membrane oxygenation post-transplant; all were weaned.
- 50% experienced deep venous thrombosis; 1 developed pulmonary embolism.
Conclusions:
- Lung transplantation demonstrated favorable early outcomes in a diverse patient group, including those with comorbidities.
- The study highlights the transforming role of lung transplantation for managing severe pulmonary complications of COVID-19.
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