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Body Mass Index and Risk of Complications After Posterior Lumbar Spine Fusion: A Matched Cohort Analysis
Daniel Alsoof1, Keir Johnson, Christopher L McDonald
1From the Department of Orthopaedics, Alpert Medical School of Brown University, Richmond St Providence, RI (Alsoof, McDonald, Daniels, and Cohen) and the Alpert Medical School of Brown University (Johnson), Richmond St Providence, RI.
Objective:
Previous studies have demonstrated that obesity is associated with increased complications after lumbar fusion. However, there are little published data on the effect of being underweight on lumbar fusion outcomes. The purpose of this study was to elucidate the effect of being underweight versus obese on outcomes after lumbar spinal fusion.
Methods:
Lumbar spinal fusion patients were identified through the PearlDiver Mariner database between 2010 and 2020. Study groups were created using International Classification of Diseases codes to identify preoperative body mass index (BMI) category as morbid obesity (BMI > 40), obesity (BMI 30 to 40), normal BMI (BMI 20 to 30), and underweight (BMI < 20) cohorts. Complications that occurred within 1 year postoperatively in this study and matched control groups were then isolated. Statistical analyses were conducted using the Pearson chi square method.
Results:
A total of 62,616 patients were identified in this analysis. This included 1,258 underweight patients (4.0%), 17,996 obese patients (57.5%), and 12,054 morbidly obese patients (38.5%). The number of patients to experience any postoperative complication was 766 (60.9%), 9,440 (52.4%), and 6,982 (57.9%) for the underweight, obese, and morbidly obese cohorts, respectively. Underweight patients showed an increased likelihood of complications related to instrumentation (odds ratio [OR] 1.85, P = 0.0237), revision fusion (OR 1.34, P = 0.04061), pulmonary complications (OR 1.43, P < 0.001), and sepsis (OR 1.91, P < 0.001). Obese patients with BMI 30 to 40 showed increased odds of the following complications: hemorrhages and hematomas (OR 1.20, P = 0.02634), surgical site complications (OR 1.27, P < 0.001), thromboembolism (OR 1.78, P < 0.001), and urinary complications (OR 1.08, P < 0.001). Morbidly obese patients with BMI > 40 showed increased odds of all complications analyzed in this study.
Conclusion:
This investigation indicates that both underweight and obese patients are at elevated risk of complications after lumbar fusion. Similar to obese patients, underweight patients may benefit from preoperative optimization by nutrition counseling to avoid potential complications.
Level Of Evidence:
III.
