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Updated: Aug 17, 2025

The Diffusion of Passive Tracers in Laminar Shear Flow
Published on: May 1, 2018
Rail induced lateral migration of particles across intact co-flowing liquids
Iwona Ziemecka1, Amaury de Hemptinne1, Vyacheslav R Misko1
1µFlow Group, Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium.
Abstract:
This paper presents a rail guided method to apply a Layer-by-Layer (LbL) coating on particles in a microfluidic device. The passive microfluidic approach allows handling suspensions of particles to be coated in the system. The trajectory of the particles is controlled using engraved rails, inducing lateral movement of particles while keeping the axially oriented liquid flow (and the interface of different liquids) undisturbed. The depth and angle of the rails together with the liquid velocity were studied to determine a workable geometry of the device. A discontinuous LbL coating procedure was converted into one continuous process, demonstrating that the chip can perform seven consecutive steps normally conducted in batch operation, further easily extendable to larger cycle numbers. Coating of the particles with two bilayers was confirmed by fluorescence microscopy.
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