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Primary pulpotomies - what should we be using?
1Dental Core Training 1, Public Dental Services, NHS Greater Glasgow and Clyde, UK.
Evidence-Based Dentistry
|December 16, 2022
Summary
Biodentine shows lower clinical and radiographic failure rates compared to formocresol in deciduous tooth pulpotomies. However, high risk of bias necessitates further research to confirm these findings for pediatric dental treatments.
Area of Science:
- Dentistry
- Pediatric Dentistry
- Regenerative Endodontics
Background:
- Formocresol has been a traditional material for pulpotomies in deciduous teeth.
- Concerns exist regarding the safety and efficacy of formocresol.
- Biodentine, a calcium silicate-based material, offers a potential alternative.
Purpose of the Study:
- To systematically review and meta-analyze the effectiveness of Biodentine versus formocresol for pulpotomies in the deciduous dentition.
- To compare clinical and radiographic outcomes between Biodentine and formocresol.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials (RCTs).
- Searched four electronic databases (Medline, Embase, Cochrane, Web of Science).
- Assessed risk of bias and used GRADE criteria for certainty of evidence.
Main Results:
- Biodentine demonstrated significantly lower clinical failure rates (RR 0.16) and radiographic failure rates (RR 0.19) at 12 months compared to formocresol.
- No significant differences were found for secondary outcomes up to 48 months.
- All outcomes were rated as low certainty due to high risk of bias.
Conclusions:
- Biodentine may be a superior material for deciduous pulpotomies compared to formocresol.
- High risk of bias in included studies limits the certainty of these findings.
- Further robust studies are required to substantiate the effectiveness of Biodentine.
