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Updated: Aug 17, 2025

A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
Published on: February 28, 2018
Gut microbiota and colorectal cancer metastasis
Zongmei Zheng1, Xinxin Hou1, Zhaoxiang Bian2
1Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Abstract:
Gut microbiota play critical roles in the development of colorectal cancer (CRC) metastasis, but the underlying mechanisms remain elusive. This review discusses the molecular mechanisms by which the gut microbiota contribute to a tumor-permissive microenvironment and facilitate malignant transformation and dissemination of tumor cells, thereby mediating CRC metastasis.
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