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Related Experiment Videos

Iodinated glycerol-induced hypothyroidism.

I H Gomolin1

  • 1Hebrew Home and Hospital, Hartford, CT 06112.

Drug Intelligence & Clinical Pharmacy
|September 1, 1987
PubMed
Summary

Iodinated glycerol, an expectorant, can cause hypothyroidism, even mild cases. Patients with prior thyroid issues should be cautious when using this iodine-based medication.

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Area of Science:

  • Endocrinology
  • Pharmacology

Background:

  • Iodinated glycerol is an organic iodine compound used as a mucolytic-expectorant.
  • Iodine compounds are known to affect thyroid function.

Observation:

  • A patient with a history of severe hypothyroidism due to potassium iodide developed subclinical hypothyroidism after taking iodinated glycerol.
  • This mirrors a previous report of goiter associated with iodinated glycerol.

Findings:

  • Iodinated glycerol can induce hypothyroidism, including subclinical forms.
  • This adverse effect is linked to the organic iodine content.

Implications:

  • Physicians should be aware of the potential for iodinated glycerol to cause hypothyroidism.
  • Iodinated glycerol should be recognized as another iodine-containing compound that can interfere with thyroid function.

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