Related Experiment Video
Updated: Aug 16, 2025

Author Spotlight: Development of a Minimally Invasive Large-Animal Model for Reliable and Reproducible Cardiovascular Research
Published on: October 20, 2023
Invasive assessment of aortic stenosis in contemporary practice
João Brito1,2, Luís Raposo1,2, Rui Campante Teles1,2
1Cardiovascular Intervention Unit, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Lisbon, Portugal.
Insights
Cardiac catheterization aids aortic stenosis assessment, complementing echocardiography. An integrated approach using both invasive and noninvasive methods offers comprehensive evaluation.
Area of Science:
- Cardiology
- Cardiovascular Imaging
- Interventional Cardiology
Background:
- Aortic stenosis diagnosis and management rely on accurate hemodynamic assessment.
- Echocardiography is the primary noninvasive tool, but limitations exist.
- Cardiac catheterization provides direct hemodynamic measurements.
Purpose of the Study:
- To review the role of cardiac catheterization in characterizing aortic stenosis.
- To discuss its clinical applications, limitations, and added value compared to echocardiography.
- To emphasize an integrative approach combining invasive and noninvasive evaluations.
Main Methods:
- Review of current literature on cardiac catheterization and echocardiography in aortic stenosis.
- Discussion of hemodynamic variables beyond transvalvular pressure gradients.
- Analysis of discrepancies between imaging and invasive measurements.
Main Results:
- Cardiac catheterization offers precise hemodynamic data, crucial for complex cases.
- Discrepancies between echocardiography and catheterization can arise and require careful interpretation.
- Hemodynamic assessment includes variables beyond simple pressure gradients.
Conclusions:
- Cardiac catheterization remains valuable for detailed aortic stenosis characterization.
- An integrative approach, combining echocardiography and catheterization, optimizes patient assessment.
- Understanding the interplay between modalities improves clinical decision-making for aortic stenosis.
Abstract:
The authors review the current role of cardiac catheterization in the characterization of aortic stenosis, its main clinical applications, its pitfalls, and its additional value to the information provided by echocardiography. Discrepancies that may arise between these two modalities are discussed and further explained. Hemodynamic variables besides transvalvular pressure drop are described, and emphasis is given to an integrative approach to aortic stenosis assessment, that includes invasive and noninvasive evaluation.
Related Concept Videos
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Aortic Regurgitation III: Medical Management
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Assessment of apical pulse
Assessing the apical pulse is a critical nursing procedure, particularly indicated for:
Mitral Stenosis II: Clinical features and Diagnostic Tests

