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DNA Replication Control: Liquid-liquid Phase Separation Comes Into Play.

Patroula Nathanailidou1, Stavros Taraviras2, Zoi Lygerou1

  • 1Department of General Biology, School of Medicine, University of Patras, Patras, Greece.

Journal of Molecular Biochemistry
|December 19, 2022
PubMed
Summary

Liquid-liquid phase separation (LLPS) may organize DNA replication. Researchers found that key replication proteins, including ORC, Cdc6, and Cdt1, can phase separate, suggesting a new regulatory mechanism for DNA replication.

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