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Boosting lignan-precursor synthesis in yeast cell factories through co-factor supply optimization

Jennifer Perrin1, Sébastien Besseau1, Nicolas Papon2

  • 1Biomolécules et Biotechnologies Végétales, Université de Tours, Tours, France.

Frontiers in Bioengineering and Biotechnology
|December 19, 2022
PubMed
Summary

No abstract available in PubMed .

Keywords:
NADPHcofactorlignanmetabolic engineeringyeast cell factories

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Polysaccharides such as glycogen and starch are synthesized from nucleoside diphosphate sugars, primarily uridine diphosphate glucose (UDPG) and adenosine diphosphate glucose (ADPG). These activated glucose donors act as key intermediates in carbohydrate metabolism and biosynthesis. UDPG primarily involves glycogen synthesis in animals and many bacteria, while ADPG plays a fundamental role in starch synthesis in plants and certain bacteria.UDPG is formed when glucose-1-phosphate reacts with...
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