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The influence of input material properties on hot melt granules prepared using a counter-rotating batch mixer

Afstathios Pafiakis1,2, Piero Armenante3, Costas G Gogos4

  • 1Bristol Myers Squibb, Pharmaceutical Manufacturing Science & Technology, New Brunswick, NJ, USA.

Pharmaceutical Development and Technology
|December 19, 2022
PubMed
Abstract

Keywords:
Hot melt granulationTwin screw granulationagglomerationfrictional energy dissipationplastic energy dissipationsinteringviscous energy dissipation

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