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A new 5'-non-coding region for human placental insulin-like growth factor II mRNA expression
Y Le Bouc1, P Noguiez, P Sondermeijer
1INSERM U 142, Hôpital Trousseau, Paris, France.
FEBS Letters
|September 28, 1987
Abstract:
A human placenta cDNA library was screened for insulin-like growth factor II (IGF-II). Four clones were selected, which exhibited an IGF-II cDNA coding sequence identical to those previously described for human adult liver IGF-II cDNA. Extensive sequence diversity was observed in the 5'-non-coding region, probably resulting from differential intron splicing.