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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Cooperative Nitrile Coordination Using Nickel and a Boron-Containing Secondary Coordination Sphere
Marissa L Clapson1, Harvey Sharma1, Joseph A Zurakowski1
1Department of Chemistry and Biochemistry, The University of Windsor, 401 Sunset Avenue, Windsor, ON, N9B 3P4, Canada.
Abstract:
Metal-ligand cooperation has emerged as a versatile tool for substrate activation in chemical reactivity. Herein, we provide the synthesis and characterization of a monoboranyl-containing analogue of the ubiquitous bulky diphosphine ligand, 1,2-bis(di-tert-butylphosphino)ethane, whose reactivity has been examined using nickel. Together, the pairing of nickel and boron provides a platform that allows for the cooperative coordination of organonitriles, giving unusual examples of intermolecularly bound dinickelacycles.
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