Related Experiment Video
Updated: Aug 16, 2025

Author Spotlight: A Focus on Standardized Salivary Gland Ultrasound Protocol in Connective Tissue Disease Research
Published on: October 13, 2023
Parotid gland keratocystoma: a rare diagnosis of a neck lump
Abethan Anparasan1, Stanislau Makaranka2, Paul Brown1
1Pathology department, Aberdeen Royal Infirmary, Aberdeen, UK.
Abstract:
Keratocystoma of the parotid gland is a rare benign tumour, with only a handful of case reports in literature. We report a case of a man in his 70s who presented to the head and neck clinic with a 2-month history of a gradually increasing left neck swelling. Fine-needle aspiration showed contents of an epidermal cyst; however, an MRI showed a solid/cystic mass with a low T2 signal, suggesting increased risk of malignancy. The patient went on to have a left superficial parotidectomy and level IIa supraselective neck dissection. The lesion contained laminated keratin and was lined by squamous epithelium, with nodal extension. Features were those of a keratocystoma; metastatic cystic well-differentiated squamous cell carcinoma was not favoured. This is the first reported case of a parotid keratocystoma with nodal extension of the lesion. This case report demonstrates that surgical excision and clinical monitoring can be a safe management strategy for these benign tumours.
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Accessory Structures of the Skin: Sebaceous Glands
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Classification of Epithelial Tissues: Glandular Epithelium
Multicellular glands are formed during early development when epithelial budding...

