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Anorectic effect of ephedrine
M R Zarrindast1, T Hosseini-Nia, F Farnoodi
1Department of Pharmacology, Faculty of Medicine, University of Tehran, Iran.
General Pharmacology
|January 1, 1987
Abstract:
1. Different doses of ephedrine (3.1-50 mg kg-1) were given intraperitoneally to rats and found to decrease food intake dose-dependently. 2. The anorectic effect of ephedrine was decreased by animal pretreatment with pimozide, but phenoxybenzamine, propranolol and methergoline did not decrease the response. 3. The results show that the anorexia produced by ephedrine may be due to indirect dopaminergic mechanism of the drug.