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Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis
Amanda E Paluch1, Shivangi Bajpai1, Marcel Ballin2
1Department of Kinesiology, Institute for Applied Life Sciences, University of Massachusetts Amherst (A.E.P., S.B., L.K.).
Circulation
|December 20, 2022
Summary
Fewer than 10,000 steps daily may lower cardiovascular disease (CVD) risk, especially for older adults. More steps progressively reduced CVD risk in those aged 60 and above.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- The optimal daily step count for cardiovascular disease (CVD) prevention is not well-defined.
- Previous research linked lower step counts to reduced all-cause mortality, but CVD-specific data is limited.
Approach:
- A meta-analysis synthesized data from eight prospective studies involving over 20,000 adults.
- Device-measured daily steps and incident CVD events (coronary heart disease, stroke, heart failure) were analyzed.
- Cox proportional hazards regression and random effects models assessed the dose-response relationship.
Key Points:
- A significant inverse association between daily steps and CVD risk was observed in adults aged 60 years and older.
- For older adults, increasing steps per day showed a progressively lower hazard ratio for CVD events.
- No significant association was found between step count quartiles and CVD risk in adults younger than 60 years.
Conclusions:
- Higher daily step counts are associated with progressively reduced CVD risk in older adults.
- Daily step monitoring offers a simple, actionable metric for CVD risk reduction in clinical and public health settings.
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