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[Postcovid cognitive impairment]
V N Shishkova1, B G Dranitsina1
1National Medical Research Center for Therapy and Preventive Medicine, Moscow, Russia.
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|December 20, 2022
Summary
Post-COVID syndrome can cause neurocognitive impairment due to central nervous system damage. Choline alfoscerate shows promise in managing these cognitive deficits and improving brain health after COVID-19.
Area of Science:
- Neurology
- Infectious Diseases
- Gerontology
Background:
- Post-COVID syndrome presents diverse complications, notably neurocognitive impairment.
- Understanding the pathogenesis of central nervous system damage is crucial for effective management.
- Factors like accelerated aging, inflammation, and reduced neuroplasticity contribute to cognitive decline.
Approach:
- Comprehensive review of current literature on post-COVID neurocognitive deficits.
- Analysis of pathogenetic mechanisms, including neuroinflammation and reduced neuroplasticity.
- Evaluation of therapeutic strategies, focusing on neuroprotective agents.
Key Points:
- Neurocognitive disorders in post-COVID syndrome are associated with accelerated cellular aging and chronic inflammation.
- Central nervous system damage and reduced neuroplasticity are key factors in post-COVID neurological complications.
- Choline alfoscerate is highlighted for its therapeutic benefits in addressing neurocognitive impairment.
Conclusions:
- Effective management of post-COVID neurocognitive impairment requires understanding its pathogenetic basis.
- Targeting mechanisms like inflammation and neuroplasticity is key.
- Choline alfoscerate therapy offers a promising avenue for improving cognitive function in post-COVID patients.
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