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Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
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Cutaneous Basal Cell Carcinoma: Does Noninvasive Ventilation Accelerate Tumor Progression?
Antonella Tammaro1, Ganiyat Adenike Ralitsa Adebanjo2, Aldo Pezzuto3
1Dermatology Department, NESMOS, Sapienza University of Rome, Rome, Italy; antonella.tammaro@uniroma1.it.
Skinmed
|December 20, 2022
Summary
Noninvasive ventilation for COVID-19 may worsen basal cell carcinoma. This treatment for coronavirus disease 2019 in COPD patients showed a dramatic progression of skin cancer lesions.
Area of Science:
- Dermatology and Respiratory Medicine
- Oncology and Infectious Diseases
Background:
- A 56-year-old female patient with chronic obstructive pulmonary disease (COPD) presented with symptoms including diarrhea, asthenia, cough, and dysgeusia.
- The patient was diagnosed with coronavirus disease 2019 (COVID-19).
Observation:
- A small basal cell carcinoma (BCC) lesion was incidentally discovered on the patient's scalp during examination.
- Following the initiation of noninvasive ventilation for COVID-19 management, a significant worsening of the BCC lesion was observed, both macroscopically and microscopically.
Findings:
- The study suggests a potential link between positive pressure noninvasive ventilation and the accelerated progression of cutaneous basal cell carcinoma.
- The observed BCC exacerbation occurred in the context of treating COVID-19 in a patient with underlying COPD.
Implications:
- Clinicians should consider the potential dermatological side effects of noninvasive ventilation, particularly in patients with pre-existing skin conditions like BCC.
- Further research is warranted to elucidate the mechanisms by which positive pressure ventilation may influence the behavior of cutaneous malignancies.
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