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Glomerulonephritis Secondary to Acute Promyelocytic Leukemia that Resolved after Induction Therapy
Carlos Andrés Regino1, José Domingo Torres2,3, Camilo Cáceres Galvis4
1Internal Medicine, Hospital Alma Mater de Antioquia, Medellín, Colombia.
Abstract:
The association of glomerulonephritis and malignant hematological disease is uncommon, but well known in chronic leukemias, lymphomas, and monoclonal gammopathies. However, only a few cases of glomerulonephritis and acute myeloid leukemia have been reported in the literature. We describe the first case of a genetically diagnosed acute promyelocytic leukemia presenting with nephrotic range proteinuria that resolved with induction therapy with ATRA and ATO and performed a comprehensive review of the literature.
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