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Properdin factor B polymorphism in four Sardinian villages
I Borelli1, E Olivetti, N Cappello
1Istituto di Genetica Medica, Università di Torino, Italy.
Human Heredity
|January 1, 1987
Abstract:
A sample of healthy unrelated individuals was typed for properdin factor B (Bf) polymorphism in four Sardinian villages. Two villages, Desulo and Tonara, are located in the highlands; the other two, Orosei and Galtellì, are located in the lowlands. No heterogeneity was found between the highland and the lowland villages, whereas a significant difference was found between the Sardinian villages and continental Italy. The allele Bf-F1 shows the highest gene frequency so far observed. Typically Sardinian is the gametic association (haplotype) HLA-A30, Cw5, B18, BfF1, DR3.