Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

278
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
278
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

337
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
337
Esophageal Perforation-II: Clinical Manifestations and Management01:28

Esophageal Perforation-II: Clinical Manifestations and Management

127
Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
127
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

186
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
186
Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

153
Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
153
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

521
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
521

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Predictors of lymph node metastases, recurrence, and survival in patients with pedunculated-type T1 colorectal cancer.

Journal of gastroenterologyยท2026
Same author

Background mucosal inflammation affects colorectal cancer prognosis in ulcerative colitis: a nationwide, multicenter study.

Journal of Crohn's & colitisยท2025
Same author

Predictors of lymph node metastases, recurrence, and survival in patients with pedunculated-type T1 colorectal cancer.

Journal of gastroenterologyยท2025
Same author

Response to Yu Yang et al.

The American journal of gastroenterologyยท2025
Same author

Correction to: Treatment Decision for Locally Resected T1 Colorectal Carcinoma-Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes.

The American journal of gastroenterologyยท2024
Same author

Novel Artificial Intelligence Combining Convolutional Neural Network and Support Vector Machine to Predict Colorectal Cancer Prognosis and Mutational Signatures From Hematoxylin and Eosin Images.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Incยท2024

Related Experiment Video

Updated: Aug 16, 2025

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

10.1K

[Multiple Intestinal Perforations Caused by Diffuse Large B-Cell Lymphoma-A Case Report].

Moe Matsumoto1, Kenta Kasahara, Yuichi Nagakawa

  • 1Dept. of Gastrointestinal and Pediatric Surgery, Tokyo Medical University.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|December 20, 2022
PubMed
Summary

This case study highlights a successful minimal surgery and early intervention for a patient with small intestine lymphoma causing gastrointestinal perforation. Early treatment led to tumor shrinkage and a favorable outcome.

More Related Videos

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
08:20

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

13.1K
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

31.9K

Related Experiment Videos

Last Updated: Aug 16, 2025

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
08:51

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch

Published on: August 24, 2019

10.1K
Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
08:20

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

13.1K
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

31.9K

Area of Science:

  • Gastroenterology
  • Oncology
  • Surgical Pathology

Background:

  • Diffuse large B-cell lymphoma (DLBCL) can present with gastrointestinal complications.
  • Small intestine lymphoma is a rare cause of intestinal perforation, often associated with poor prognosis.

Observation:

  • An 83-year-old male diagnosed with DLBCL developed abdominal pain due to a gastrointestinal perforation.
  • Computed tomography confirmed small intestine perforation, necessitating emergency surgical resection.

Findings:

  • Postoperative R-CHOP therapy resulted in significant tumor shrinkage.
  • The patient experienced a successful outcome following minimal surgery and early postoperative intervention.

Implications:

  • This case demonstrates the feasibility of successful management for small intestine lymphoma with intestinal perforations.
  • Early diagnosis and intervention, combined with appropriate chemotherapy, can improve outcomes in such critical cases.