Related Experiment Video
Updated: Aug 16, 2025
08:50
Technique and Patient Selection Criteria of Right Anterior Mini-Thoracotomy for Minimal Access Aortic Valve Replacement
Published on: March 26, 2018
11.8K
Tranexamic Acid Use Intra-Operatively Decreases the Need for Blood Transfusions and Post-Operative Edema in
Bayan Entezari1, Larry M Wolford2, Daniel C Gunn3,4
1Medicine, Texas A&M College of Medicine, Dallas, USA.
Cureus
|December 21, 2022
Summary
Tranexamic acid (TXA) effectively reduced blood loss and tissue edema in patients undergoing major temporomandibular joint (TMJ) replacement surgeries. This study highlights TXA
Area of Science:
- Oral and Maxillofacial Surgery
- Anesthesiology
- Pharmacology
Background:
- Temporomandibular joint (TMJ) surgeries encompass diverse procedures, with potential complications including significant bleeding and edema.
- Tranexamic acid (TXA), an antifibrinolytic agent, is recognized for its efficacy in reducing blood loss in orthopedic settings.
Observation:
- A study observed five patients undergoing major TMJ replacement surgeries.
- TXA was administered during these surgical procedures.
Findings:
- TXA administration was associated with reduced blood loss during TMJ replacement surgery.
- TXA also appeared to mitigate postoperative tissue edema.
Implications:
- TXA may be a valuable adjunct for managing bleeding and swelling in TMJ replacement surgeries.
- Further research can explore optimal TXA protocols for maxillofacial procedures.
Related Concept Videos
01:18Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
1.3K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.3K
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
827
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
827
01:29Venous Thrombosis III: Interprofessional Care
16
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
16
01:18Effects of EDTA on End-Point Detection Methods
322
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
322
01:26Tonsillitis II: Management
157
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
157
01:22Aneurysm IV: Nursing Management
16
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
16