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Eikenella corrodens in human bites
Abstract:
Eikenella corrodens, a gram negative rod, was cultured in about one third of 24 patients with human bite wounds. The organism was sensitive to penicillin but not to methicillin. Clinically the infections in which Eikenella corrodens were found were not different from other infections. Because of the variety of possible pathogens in human bite infections, we start the patients on a broad spectrum antibiotic while awaiting the results of the culture and sensitivity. However, antibiotics alone are not sufficient treatment in HBI; 20 of 24 patients in this series required surgical drainage. Surgical treatment consists of thorough exploration, exteriorization and excision of devitalized tissues. Complications were more frequent in sutured wounds, or when surgical drainage was delayed.
Insights
Eikenella corrodens was found in one-third of human bite wound infections. Penicillin was effective, but antibiotics alone were insufficient; surgical drainage was crucial for healing.
Area of Science:
- Infectious Diseases
- Microbiology
- Surgical Infections
Background:
- Human bite wounds present a polymicrobial challenge.
- Eikenella corrodens is a potential pathogen in these infections.
Purpose of the Study:
- To investigate the prevalence and characteristics of Eikenella corrodens in human bite wound infections.
- To evaluate the clinical significance and treatment of Eikenella corrodens in human bite wounds.
Main Methods:
- Prospective study of 24 patients with human bite wounds.
- Bacterial culturing and antibiotic sensitivity testing.
- Clinical assessment and surgical intervention evaluation.
Main Results:
- Eikenella corrodens was identified in approximately 33% of cases.
- The organism demonstrated sensitivity to penicillin but resistance to methicillin.
- Infections with Eikenella corrodens were clinically indistinguishable from other bite wound infections.
- 20 out of 24 patients required surgical drainage.
Conclusions:
- Eikenella corrodens is a relevant pathogen in human bite wound infections.
- While penicillin is effective, broad-spectrum antibiotics are initially necessary due to polymicrobial nature.
- Surgical drainage is essential for managing these infections; delayed drainage and wound suturing increase complication risks.