Related Experiment Video
Updated: Aug 16, 2025
07:41
Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction
Published on: June 7, 2011
52.4K
Coronary Intravascular Lithotripsy
Jayakumar Sreenivasan1, Avisha Shah2, Tanawan Riangwiwat3
1From the Section of Cardiovascular Medicine, Yale School of Medicine, New Haven, CT.
Cardiology in Review
|December 21, 2022
Summary
Coronary artery calcification poses risks and challenges for cardiac procedures. Coronary intravascular lithotripsy (IVL) offers a safe, effective new method to treat calcified arteries before percutaneous coronary intervention (PCI).
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Coronary artery calcification is a significant risk factor for adverse cardiac events.
- Severe calcification complicates percutaneous coronary intervention (PCI) by hindering device delivery and stent expansion.
- Existing treatments for coronary calcification have limitations and potential complications.
Approach:
- Coronary intravascular lithotripsy (IVL) is a novel technique using acoustic pressure waves to modify arterial calcification.
- The IVL device is user-friendly, minimizing the learning curve for interventional cardiologists.
- Prospective studies demonstrate IVL's safety and efficacy in preparing calcified lesions for PCI.
Key Points:
- IVL effectively modifies severely calcified coronary stenoses, facilitating optimal stent deployment.
- This technique can be used as a standalone therapy or adjunctively with other calcium modification tools.
- Compared to traditional methods, IVL may reduce serious procedural complications during PCI.
Conclusions:
- Coronary IVL is a promising technology for managing complex coronary artery calcification.
- Further long-term clinical outcome data is needed to fully establish the benefits of IVL-facilitated PCI.
- IVL has the potential to improve PCI success rates and patient outcomes in calcified coronary lesions.
Related Concept Videos
01:25Urinary Tract Calculi VI: Surgical Management
19
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
19
01:27Coronary Artery Disease V: Interprofessional Care
22
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
22
01:28Acute Coronary Syndrome IV: Interprofessional Care
20
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
20
01:27Peripheral Artery Disease III: Interprofessional Care
19
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
19
01:30Acute Coronary Syndrome III: Diagnostic Studies
20
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
20
01:28Cardiac Catheterization I: Pre-Procedure Overview
112
Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
112