Developing an Australian utility value set for MacNew-7D health states

Area of Science:

• Health Economics
• Cardiology
• Quality of Life Measurement

Background:

• A new preference-based measure, MacNew-7D, aids quality of life assessment in cardiology health economic evaluations.
• A general population value set for MacNew-7D was lacking.
• This study aimed to develop a population utility value set for the MacNew-7D instrument.

Purpose of the Study:

• To develop a population utility value set for the MacNew-7D heart disease-specific instrument.
• To enable accurate quality-adjusted life years (QALYs) estimation in health economic evaluations.
• To establish a generalizable value set for the Australian population.

Main Methods:

• Discrete Choice Experiments (DCE) technique employed for preference elicitation.
• Online survey with quota sampling (age, sex, jurisdiction) for Australian population representativeness.
• 200 choice sets per respondent (8 task sets + 2 quality control sets); best-fitting models selected based on consistency, parsimony, and goodness of fit.

Main Results:

• 1903 respondents analyzed.
• MacNew-7D utility values ranged from -0.4456 to 1.000.
• Best-fitting model retained most levels; findings robust to sensitivity analyses.

Conclusions:

• The developed MacNew-7D utility value set is suitable for estimating QALYs in cardiology.
• The value set is derived from an Australian population sample.
• Generalizability to dissimilar populations may be limited.