Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Carbohydrate Metabolism

Carbohydrate Metabolism

Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Diabetes: Symptoms, Diagnosis, and Complications

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...

Diabetes Mellitus: Overview and Type I Subtype

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Is strength training more effective than aerobic exercise for improving glycaemic control and body composition in people with normal-weight type 2 diabetes? Reply to Pontes‑Silva A, Santos‑de‑Araujo AD, Teixeira BC et al [letter].

Diabetologia·2024

Same author

Chemerin Levels in Individuals with Type 2 Diabetes and a Normal Weight versus Individuals with Type 2 Diabetes and Obesity: An Observational, Cross-Sectional Study.

Biomedicines·2024

Same author

Correction to: Strength training is more effective than aerobic exercise for improving glycaemic control and body composition in people with normal-weight type 2 diabetes: a randomised controlled trial.

Diabetologia·2024

Same author

[Biosynthesis of immunosuppressant tacrolimus: a review].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology·2023

Same author

Tafolecimab in Chinese Patients With Hypercholesterolemia (CREDIT-4): A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial.

JACC. Asia·2023

Same author

Neural pathways of attitudes toward foreign languages predict academic performance.

Frontiers in psychology·2023

Search research articles

Related Experiment Video

Updated: Aug 16, 2025

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

Effectiveness of a Community-Based Structured Physical Activity Program for Adults With Type 2 Diabetes: A Randomized

Aishee B Mukherji¹, Di Lu², FeiFei Qin²

¹Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, California.

JAMA Network Open

|December 21, 2022

Summary

Structured exercise, thrice weekly, improved type 2 diabetes control (HbA1c) in a community setting for adherent participants. Adherence is key for exercise interventions to effectively manage diabetes.

More Related Videos

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults

Published on: December 9, 2014

A Training Program Using an Agility Ladder for Community-Dwelling Older Adults

A Training Program Using an Agility Ladder for Community-Dwelling Older Adults

Published on: March 7, 2020

Related Experiment Videos

Last Updated: Aug 16, 2025

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults

Published on: December 9, 2014

A Training Program Using an Agility Ladder for Community-Dwelling Older Adults

A Training Program Using an Agility Ladder for Community-Dwelling Older Adults

Published on: March 7, 2020

Area of Science:

Community health
Exercise physiology
Diabetes management

Background:

Physical activity interventions are effective for type 2 diabetes, but community-based implementation needs exploration.
Translating exercise findings into community settings is crucial for broader diabetes management.

Purpose of the Study:

To assess the effectiveness of varying weekly structured exercise frequencies on diabetes control.
To evaluate community-based exercise programs for individuals with type 2 diabetes.

Main Methods:

A randomized controlled trial (IMPACT study) compared once-weekly, thrice-weekly exercise, and usual care (UC) for 6 months.
Participants with type 2 diabetes (HbA1c 6.5%-13.0%) attended community fitness centers for exercise.
Primary outcome was HbA1c change at 6 months, with intention-to-treat and per-protocol analyses.

Main Results:

Intention-to-treat analysis showed no significant HbA1c difference between groups.
Per-protocol analysis revealed a significant HbA1c reduction (-0.38%) in the thrice-weekly group compared to UC.
Adherence to at least 50% of sessions in the thrice-weekly group correlated with improved HbA1c.

Conclusions:

Thrice-weekly exercise improved HbA1c in adherent participants with type 2 diabetes in a community setting.
Future interventions should prioritize adherence to structured exercise programs to meet recommended guidelines.
Community-based exercise can be a viable strategy for diabetes management when adherence is achieved.