Next-generation RSV vaccines avoid flipping out

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Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
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Mark E Peeples1,2

  • 1Center for Vaccines and Immunity, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.

Science Translational Medicine
|December 21, 2022
PubMed

Abstract:

In clinical trials, RSV prefusion F protein induced higher neutralizing antibodies and more activated memory B cells than postfusion F protein (Chang et al.).

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