Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Improving Translational Accuracy02:07

Improving Translational Accuracy

11.8K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
11.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Predefined-time distributed optimal formation control for constrained UAV-UGV systems.

ISA transactions·2026
Same author

A Multitask Crisscross Network for One-Shot Bearing Multiattribute Fault Diagnosis.

IEEE transactions on cybernetics·2026
Same author

Synchronous stability analysis and enhancement method for grid connected inverters in weak grids.

Scientific reports·2026
Same author

S100A11 regulates microglial inflammatory response in neuropathic pain via H3K27ac-TFEB-mitochondrial autophagy axis.

The journal of headache and pain·2026
Same author

Reinforcement Learning-Based Fuzzy Control for Nonlinear Systems With Unknown Dynamics via Parallel Composite Policy Iteration Scheme.

IEEE transactions on cybernetics·2026
Same author

GA-Enhanced Control for Autonomous Vehicles: Coordinating FlexRay Protocol Under Randomly Perturbed Sampling Periods.

IEEE transactions on cybernetics·2026

Related Experiment Video

Updated: Aug 16, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.3K

Improving COVID-19 CT classification of CNNs by learning parameter-efficient representation.

Yujia Xu1, Hak-Keung Lam1, Guangyu Jia1

  • 1Department of Engineering, King's College London, Strand, London, WC2R 2LS, United Kingdom.

Computers in Biology and Medicine
|December 21, 2022
PubMed
Summary

This study introduces novel data augmentation and similarity regularization techniques to improve COVID-19 detection from CT scans. These methods enhance the accuracy and sensitivity of deep learning models, surpassing previous state-of-the-art performance.

Keywords:
CNNsCOVID-19Computed tomographyDeep learningSimilarity regularization

More Related Videos

Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique
04:48

Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique

Published on: July 5, 2024

480
DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning
04:17

DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning

Published on: May 10, 2024

842

Related Experiment Videos

Last Updated: Aug 16, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.3K
Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique
04:48

Swin-PSAxialNet: An Efficient Multi-Organ Segmentation Technique

Published on: July 5, 2024

480
DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning
04:17

DNA Virus Detection System Based on RPA-CRISPR/Cas12a-SPM and Deep Learning

Published on: May 10, 2024

842

Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computer Science

Background:

  • The COVID-19 pandemic necessitates rapid and accurate diagnostic tools.
  • Computed tomography (CT) imaging is vital for COVID-19 diagnosis.
  • Existing deep learning models face challenges with data diversity, accuracy, and sensitivity.

Purpose of the Study:

  • To enhance data diversity in COVID-19 CT datasets.
  • To improve the accuracy and sensitivity of deep learning models for COVID-19 detection.
  • To develop parameter-efficient representations for Convolutional Neural Networks (CNNs).

Main Methods:

  • Designed incremental data augmentation techniques for CT images.
  • Applied similarity regularization (SR) derived from contrastive learning.
  • Trained and evaluated seven common CNNs on the COVIDx CT-2A dataset.

Main Results:

  • Augmentation and SR techniques consistently improved CNN performance.
  • DenseNet121 with SR achieved 99.44% accuracy in three-category classification.
  • Achieved 98.40% precision, 99.59% sensitivity, and 99.50% specificity for COVID-19 pneumonia.

Conclusions:

  • The proposed augmentation and SR methods significantly enhance COVID-19 detection accuracy.
  • The approach surpasses existing state-of-the-art methods on the COVIDx CT-2A benchmark dataset.
  • The developed techniques offer a promising direction for improving AI-assisted medical diagnosis.