Related Experiment Videos
Primary hyperparathyroidism in dogs: 21 cases (1976-1986)
1Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616.
Journal of the American Veterinary Medical Association
|August 1, 1987
Summary
Hyperparathyroidism in older dogs often involves parathyroid tumors. Surgical removal can lead to hypocalcemia, requiring careful monitoring and management for successful outcomes.
Area of Science:
- Veterinary Medicine
- Endocrinology
- Oncology
Background:
- Hyperparathyroidism is a condition affecting older dogs, often linked to parathyroid tumors.
- Clinical signs include polydipsia/polyuria, listlessness, and muscle weakness.
- Serum calcium levels were significantly elevated, ranging from 12.1 to 19.6 mg/dl.
Purpose of the Study:
- To evaluate clinical findings, treatment outcomes, and long-term prognosis for dogs with hypercalcemia and hyperparathyroidism.
- To analyze the effects of parathyroid tumor removal on calcium levels and clinical status.
- To assess the incidence of complications, such as hypocalcemia and iatrogenic hypercalcemia.
Main Methods:
- Retrospective case review of 21 dogs diagnosed with hypercalcemia and hyperparathyroidism.
- Analysis of clinical signs, serum biochemistry (calcium, phosphorus, BUN), and histopathology.
- Evaluation of surgical outcomes following parathyroid tumor excision and medical management.
Main Results:
- Twenty dogs had parathyroid adenomas, and one had a carcinoma.
- Post-surgery, 11 of 19 dogs experienced hypocalcemia, with 9 developing clinical signs.
- Iatrogenic hypercalcemia occurred in 7 of 16 dogs treated with calcium carbonate and vitamin D.
Conclusions:
- Surgical removal of parathyroid tumors is effective but can lead to post-operative hypocalcemia.
- Careful monitoring and management are crucial for dogs recovering from parathyroid surgery.
- Long-term survival is achievable, with most deaths occurring due to unrelated conditions.