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Updated: Aug 16, 2025

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors

Jian Yao1, Yudong Yin1, Hong Han2

  • 1State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Collaborative Innovation Center for Guangxi Ethnic Medicine, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, PR China.

European Journal of Medicinal Chemistry
|December 21, 2022
PubMed

Keywords:
DeacetylaseMolecular dockingSIRT5 inhibitorsSirtuinsStructure-activity relationship

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