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Systemic paecilomycosis in a dog.

M P Littman¹, M H Goldschmidt

¹Department of Clinical Studies-Philadelphia, University of Pennsylvania School of Veterinary Medicine 19104-6010.

Journal of the American Veterinary Medical Association

|August 15, 1987

Summary

Disseminated paecilomycosis, a fungal infection, was diagnosed in a healthy adult dog. The study highlights Paecilomyces variotii as a potentially more virulent pathogen than previously recognized in veterinary medicine.

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Area of Science:

Veterinary Mycology
Infectious Diseases in Animals

Background:

Paecilomyces variotii is a fungus typically associated with mild infections.
Immunocompetent hosts are generally considered resistant to disseminated Paecilomyces infections.

Observation:

An adult dog without immunosuppressive disease presented with a 3-month history of illness.
Clinical signs included ulcerative granulomatous lymphadenitis, fever, anorexia, dyspnea, generalized lymphadenopathy, retinochoroiditis, and seizures.

Findings:

Disseminated paecilomycosis was diagnosed antemortem.
Histological examination and fungal culture identified Paecilomyces variotii from lymph node samples.
The dog had no underlying conditions predisposing it to infection.

Implications:

Paecilomyces variotii may possess greater pathogenic potential in dogs than previously understood.
This case suggests the need for increased awareness of Paecilomyces variotii as a cause of severe fungal infections in immunocompetent animals.
Further research into the pathogenicity and host-pathogen interactions of Paecilomyces variotii is warranted.

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