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TUBULOINTERSTITIAL NEPHRITIS WITH UVEITIS (TINU SYNDROME). A CASE REPORT
Summary
This case report details a 50-year-old woman diagnosed with tubulointerstitial nephritis with uveitis syndrome (TINU). Steroid treatment effectively reduced proteinuria and stabilized kidney function.
Area of Science:
- Nephrology
- Ophthalmology
- Rheumatology
Background:
- Persistent fever and elevated C-reactive protein post-respiratory infection prompted specialist referral.
- Extensive investigations including multi-specialty consultations and advanced imaging were performed.
Observation:
- Rapidly progressing renal insufficiency with active urinary sediment was noted.
- Bilateral anterior uveitis developed two months after initial renal findings.
Findings:
- Renal biopsy confirmed tubulointerstitial nephritis.
- Genetic testing confirmed the diagnosis of tubulointerstitial nephritis with uveitis syndrome (TINU).
Implications:
- Steroid therapy led to gradual reduction in proteinuria.
- Steroid treatment stabilized the patient's renal function, highlighting treatment efficacy for TINU.
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