Related Experiment Video For Cervical cancer
Updated: Aug 16, 2025
Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
Histologıcal results of HPV genotyping from a colposcopy center
Sevgi Koc1, Dilek Yuksel2, Tugba Kinay3
1Department of Gynecologic Oncology, University of Health Sciences Turkey, Etlik Zubeyde Hanim Women's Health Education and Research Hospital, Ankara, Turkey. drskoc@hotmail.com.
Purpose:
To investigate the role of partial human papillomavirus (HPV) genotyping tests in predicting the diagnosis of high-grade cervical intraepithelial lesion and cancer (HSIL +) as a result of colposcopic histopathology.
Materials And Methods:
The study included 2872 patients who presented at our colposcopy unit between January 1, 2015 and December 31, 2019 and underwent colposcopy for the first time. The patients were compared in terms of HSIL + results as HPV 16/18 and HPV other type positive groups.
Results:
HSIL + was determined at the rate of 22.3% in the HPV 16/18 group and at 7.0% in the HPV Other group, and the difference was statistically significant (p = 0.000). HPV 16/18 types were found to be responsible for 84.8% of cervical cancers and 83.5% of HSIL and worse cases.
Conclusion:
Partial HPV 16/18 genotyping is an effective strategy in the triage of HPV-positive women. HPV type identification consistent with the epidemiology of HPV types in HSIL + cases in the screened population, and the age-appropriate use of primary HPV tests will determine the sensitivity and cost effectiveness of screening.
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