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Diffusion-Weighted Imaging for Detecting Glufosinate Ammonium Intoxication: A Case Report.

Hyoung Yeob Kim, Noh Hyuk Park

Journal of the Korean Society of Radiology

|December 22, 2022

Summary

Glufosinate ammonium herbicide poisoning can cause severe brain swelling. A case report details cytotoxic edema in specific brain regions on MRI after intentional glufosinate ammonium ingestion.

Keywords:

Glufosinate Ammonium Herbicides Magnetic Resonance Imaging Poisoning

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Area of Science:

Neurology
Toxicology
Radiology

Background:

Glufosinate ammonium herbicides are widely used non-selective agents.
Increased herbicide use correlates with rising cases of acute intoxication, often from suicide attempts.

Observation:

A patient presented with symptoms following glufosinate ammonium intoxication.
Brain diffusion-weighted MRI revealed specific abnormalities.

Findings:

The patient exhibited cytotoxic edema.
Affected areas included the posterior limbs of bilateral internal capsules, bilateral middle cerebellar peduncles, and splenium of the corpus callosum.

Implications:

This case highlights a potential neurotoxic effect of glufosinate ammonium.
Diffusion-weighted MRI is crucial for diagnosing and characterizing brain injury in glufosinate ammonium poisoning.
Understanding these MRI findings aids in clinical management and prognosis assessment.