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Childhood Guillain-Barre syndrome in the SARS-CoV-2 era: Is there any causative relation?
Elham Pourbakhtyaran1, Morteza Heidari1,2, Masood Ghahvechi Akbari3
1Department of Pediatric Neurology, Pediatrics Center of Excellence, Children's Medical Center Tehran University of Medical Sciences Tehran Iran.
Abstract:
We reported an association between SARS-CoV-2 infection and Guillain-Barre syndrome (GBS). From 37 patients with GBS, previous SARS-CoV-2 clinical clues, including fever, cough, and diarrhea, were recorded in 18 patients. Among them, SARS-CoV-2 IgG was detected in seven patients, considered confirmed as cases. SARS-CoV-2 PCR was positive in just one patient. Although we found no increase in patient recruitment during the pandemic compared to previous years, our study indicated that SARS-CoV-2 is associated with poorer outcomes regarding GBS disability scale and hospital stay.
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