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Updated: Aug 16, 2025

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Neurodevelopment at seven years and parents' feelings of prematurely born children

Clémentine Mercier1, Hélène Deforge1,2, Jean-Michel Hascoët1,2

  • 1Division of Neonatology, Maternité Régionale Universitaire, CHRU - NANCY, Nancy, France.

Frontiers in Pediatrics
|December 22, 2022
PubMed

Insights

Half of very premature babies experience long-term neurodevelopmental issues, impacting their quality of life. These children often have visual impairments and behavioral disorders, affecting family well-being.

Area of Science:

  • Neonatal Medicine
  • Developmental Pediatrics
  • Public Health

Background:

  • Advances in neonatal resuscitation improve survival rates for very premature infants.
  • Long-term neurodevelopmental outcomes and cognitive abilities in these children remain a concern.

Purpose of the Study:

  • To assess neurodevelopment and learning in 7-year-olds born prematurely.
  • To evaluate parental perceptions of quality of life at age 8.

Main Methods:

  • Analysis of data from 238 children born before 33 weeks gestation.
  • Neurodevelopmental assessment included cerebral palsy, hearing/visual impairment, and behavioral disorders.
  • School performance evaluated by EDA test; parental feelings assessed via questionnaire.

Main Results:

  • 51% of children exhibited neurodevelopmental abnormalities at age 7.
  • Lower gestational age and neonatal EEG abnormalities correlated with adverse outcomes.
  • 39% of parents of affected children reported a significant impact on quality of life.

Conclusions:

  • A significant proportion of very premature infants face long-term neurodevelopmental challenges.
  • These challenges substantially affect the quality of life for both the child and their family.
Abstract

Keywords:
extreme prematurityneurodevelopmental abnormalitiesparental feelingsperinatal networkquality of life

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