Related Experiment Video
Updated: Aug 16, 2025
07:20
Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
14.0K
Bimetallic Nickel Complexes Supported by a Planar Macrocyclic Diphosphoranide Ligand
Andie R Delaney1, Li-Juan Yu1, Vincent Doan1
1Research School of Chemistry, Australian National University, Canberra, ACT, 2601, Australia.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|December 22, 2022
Summary
Researchers developed a novel nickel-promoted macrocyclic ligand capable of supporting dinickel complexes for catalysis. This versatile ligand scaffold allows tuning of catalytic architectures by adjusting substituents and conditions.
Area of Science:
- Coordination Chemistry
- Catalysis
- Supramolecular Chemistry
Background:
- Metal-metal cooperativity is a key strategy in catalysis, necessitating ligands that can bridge multiple metal centers.
- Designing scaffolds for supporting bimetallic complexes is crucial for advancing cooperative catalytic processes.
Purpose of the Study:
- To synthesize a novel dinucleating planar macrocyclic ligand.
- To explore the coordination chemistry of this ligand with nickel, forming bimetallic dinickel(II) and dinickel(I) complexes.
- To investigate the tunability of the ligand scaffold for different architectures.
Main Methods:
- Nickel-promoted macrocyclization reaction.
- Synthesis and characterization of dinickel complexes.
- Systematic variation of ligand substituents and reaction conditions.
Main Results:
- Successful formation of a dinucleating planar macrocyclic ligand.
- Isolation and characterization of bimetallic dinickel(II) and dinickel(I) complexes.
- Demonstration of tunable reaction outcomes yielding dinucleating macrocyclic, mononucleating macrocyclic, or pincer architectures.
Conclusions:
- The developed nickel-promoted macrocyclic ligand is a versatile scaffold for supporting bimetallic complexes.
- Ligand design and reaction condition optimization allow control over the resulting complex architecture and potential catalytic applications.
- This work provides a new platform for exploring metal-metal cooperativity in catalysis.
More Related Videos
Related Concept Videos
02:42Valence Bond Theory
9.0K
Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
9.0K
02:51Metal-Ligand Bonds
21.3K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
21.3K
02:57Coordination Number and Geometry
16.4K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
16.4K
01:09Complexation Equilibria: Factors Influencing Stability of Complexes
448
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
448
00:43Complexometric Titration: Ligands
1.1K
Different monodentate and polydentate ligands are used as complexing agents in complexometric titration reactions. The formation of complexes by mono- and bidentate ligands involves two or more intermediate steps, limiting their use as complexing agents. In comparison, polydentate ligands can form complexes with metal ions in a single-step process, facilitating sharper end points. This means polydentate ligands, such as amino carboxylic acid derivatives, are most commonly employed in...
1.1K
01:19Complexation Equilibria: The Chelate Effect
596
In complexation reactions, metal atoms or cations interact with ligands to form donor-acceptor adducts called metal complexes. Ligands that bind through one donor site are monodentate, ligands with two donor sites are bidentate, and those with more than two donor sites are polydentate ligands. For example, ethylene diamine is a bidentate ligand that binds through two nitrogen donor atoms, forming a five-membered ring. EDTA is a polydentate ligand that binds through four oxygen and two nitrogen...
596