Newton's law of gravitation describes the gravitational force between any two point masses. However, for extended spherical objects like the Earth, the Moon, and other planets, the law holds with an assumption that masses of spherical objects are concentrated at their respective centers.
This assumption can be proved easily by showing that the expression for gravitational potential energy between a hollow sphere of mass (M) and a point mass (m) is the same as it would be for a pair of extended...

Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.

In the years before Newton, a general belief prevailed that different laws governed objects in the sky than objects on Earth. When Kepler wrote down the three laws of planetary motion, explaining in detail the geometrical properties of the planetary orbits around the Sun, there was no immediate idea to discern their connection with more fundamental laws. It was Isaac Newton who, in 1665–66, figured out the connection between planetary motion, the motion of the moon around the Earth, and...

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

Photoluminescence offers a wide range of applications due to its inherent sensitivity and selectivity. This technique allows for both direct and indirect analyses of the analyte. Direct quantitative analysis is possible when the analyte exhibits a favorable quantum yield for fluorescence or phosphorescence. However, an indirect analysis may be feasible if the analyte is not fluorescent or phosphorescent, or if the quantum yield is unfavorable. Indirect methods include reacting the analyte with...

Thousands of artificial satellites orbit the Earth every day at various distances from the Earth. Satellites that orbit the Earth below an altitude of 1,600 km are considered to be orbiting in low-Earth orbit (LEO). Research satellites and Earth observation satellites are usually placed in LEO, and mostly orbit the Earth in elliptical orbits. Navigation satellites are placed in medium-Earth orbit (MEO), ranging from 2,000 km to 36,000 km from the surface of the Earth. Meanwhile, communication...