Host-Selective Phytotoxins Incorporating the Epoxy-Triene-Decacarboxylate Moiety Function through the Hijacking of
Minoru Ueda1, Nobuki Kato1, Yoshinori Kurata1
1Graduate School of Science, Tohoku University, 6-3, Aramaki-Aza-Aoba, Aoba-ku, Sendai 980-8578, Japan.
Abstract:
Host selective toxins (HSTs) are small molecule phytotoxins that control the pathogenicity of microbes in the host plant, but the mechanistic basis for their selectivity is unknown. We developed AcIle-EDA (Aclle-(+)-9,10-epoxy-8-hydroxy-9-methyldeca-trienoic acid) as a molecular probe of an HST, examined its mode of action in genetically modified Oryza sativa, and found it to trigger ROS production through NADPH-oxidase OsRBOHB, causing the emergence of pathogenic traits. This result strongly suggests that AcIle-EDA functions through the hijacking of the plant-microbe interaction system.
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