Evaluation of Pediatric Patients with a Diagnosis of Ureterocele

Özgür Özdemir Şimşek1, Sibel Tiryaki2, Gökçen Erfidan1

  • 1Department of Pediatric Nephrology, Faculty of Medicine Tepecik Training and Research Hospital, University of Health Sciences, Izmir 35170, Turkey.

Pediatric Reports
|December 22, 2022
PubMed

Insights

This study found no clear criteria for using voiding cystourethrography in children with ureterocele. Vesicoureteric reflux (VUR) did not correlate with increased kidney damage in these patients.

Area of Science:

  • Pediatric Nephrology
  • Urology

Background:

  • Ureteroceles are congenital anomalies that can lead to urinary tract infections (UTIs) and vesicoureteric reflux (VUR).
  • The clinical significance of VUR in patients with ureteroceles, particularly those with a double collecting system, remains unclear.
  • The role of voiding cystourethrography (VCUG) in managing ureteroceles is not well-defined.

Purpose of the Study:

  • To evaluate the incidence of UTIs and VUR in pediatric patients diagnosed with ureterocele.
  • To investigate the association between VUR and clinical outcomes such as kidney damage and need for surgery.
  • To assess the utility of VCUG in the management of ureterocele.

Main Methods:

  • Retrospective evaluation of pediatric patients diagnosed with ureterocele between 2012 and 2022.
  • Data collected included demographic, clinical, and laboratory findings, focusing on UTI history and VUR.
  • Analysis of VCUG findings in relation to clinical presentation and outcomes.

Main Results:

  • Twenty-four children with ureterocele were included; 54.2% presented with antenatal hydronephrosis and 37.5% with UTI.
  • VUR was present in 11 patients (45.8%), with severe VUR (≥stage 3) in 9 (37.5%).
  • VUR was associated with female gender and UTI history, but not with ipsilateral hydronephrosis, renal scarring, or surgical intervention.

Conclusions:

  • No specific criteria were identified to guide the selection of patients with ureterocele for VCUG.
  • VUR did not appear to cause additional kidney damage in this cohort.
  • Further research is needed to establish optimal management strategies for pediatric ureterocele cases.

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