Reported Side or Adverse Effects Associated with Medication Nonadherence Among Adolescents and Young Adults with
Lucy Barnard-Brak1, Carolina Kudesey1
1Department of Special Education and Multiple Abilities, The University of Alabama System, Tuscaloosa, Alabama, USA.
Journal of Child and Adolescent Psychopharmacology
|December 22, 2022
Summary
For adolescents and young adults with attention-deficit/hyperactivity disorder (ADHD), specific side effects like upset stomach and vomiting, not the overall number or severity, predict medication nonadherence. Healthcare providers should monitor these symptoms.
Area of Science:
- Psychiatry
- Pediatrics
- Pharmacology
Background:
- Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder affecting adolescents and young adults.
- Medication adherence is crucial for managing ADHD symptoms but is often challenging in this population.
- Understanding factors influencing medication nonadherence is essential for improving treatment outcomes.
Purpose of the Study:
- To identify specific side effects associated with medication nonadherence in adolescents and young adults diagnosed with ADHD.
- To investigate the relationship between the number and severity of side effects and medication nonadherence.
- To determine if particular side effects are stronger predictors of nonadherence than others.
Main Methods:
- Survey data from 157 adolescents and young adults with ADHD were analyzed.
- Multiple linear regression and chi-square automatic interaction detection techniques were employed.
- The study examined reported side effects and self-reported medication adherence.
Main Results:
- The average participant reported 10.33 side effects, with 77% experiencing at least one.
- Neither the total number nor the overall severity of side effects significantly correlated with medication nonadherence.
- The severity of specific side effects, namely upset stomach and vomiting, showed a significant association with medication nonadherence.
Conclusions:
- Healthcare providers should consider upset stomach and vomiting as key indicators of potential medication nonadherence in young ADHD patients.
- Targeted interventions addressing these specific side effects may improve medication adherence rates.
- This finding highlights the importance of detailed symptom monitoring beyond general side effect burden.
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