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Published on: December 21, 2019
Considerations for Imaging of Malignant Pleural Mesothelioma: A Consensus Statement from the International
Sharyn I Katz1, Christopher M Straus2, Leonid Roshkovan1
1Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Abstract:
Malignant pleural mesothelioma (MPM) is an aggressive primary malignancy of the pleura that presents unique radiologic challenges with regard to accurate and reproducible assessment of disease extent at staging and follow-up imaging. By optimizing and harmonizing technical approaches to imaging MPM, the best quality imaging can be achieved for individual patient care, clinical trials, and imaging research. This consensus statement represents agreement on harmonized, standard practices for routine multimodality imaging of MPM, including radiography, computed tomography, 18F-2-deoxy-D-glucose positron emission tomography, and magnetic resonance imaging, by an international panel of experts in the field of pleural imaging assembled by the International Mesothelioma Interest Group. In addition, modality-specific technical considerations and future directions are discussed. A bulleted summary of all technical recommendations is provided.
Insights
Standardizing imaging techniques for malignant pleural mesothelioma (MPM) improves disease assessment. This consensus provides harmonized practices for multimodality imaging in MPM diagnosis and management.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Malignant pleural mesothelioma (MPM) is a challenging cancer to image accurately.
- Current imaging lacks standardized approaches for staging and follow-up.
Purpose of the Study:
- To establish harmonized, standard practices for multimodality imaging of MPM.
- To improve the quality and reproducibility of imaging for MPM patient care, clinical trials, and research.
Main Methods:
- Consensus statement developed by an international panel of experts from the International Mesothelioma Interest Group.
- Review and harmonization of technical approaches for routine multimodality imaging of MPM.
Main Results:
- Agreement on standard practices for radiography, computed tomography (CT), 18F-2-deoxy-D-glucose positron emission tomography (FDG-PET), and magnetic resonance imaging (MRI).
- Discussion of modality-specific technical considerations and future research directions.
Conclusions:
- Harmonized imaging practices are crucial for accurate MPM assessment.
- Standardized multimodality imaging will enhance patient care, clinical trials, and research in MPM.
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