Considerations for Imaging of Malignant Pleural Mesothelioma: A Consensus Statement from the International

Sharyn I Katz1, Christopher M Straus2, Leonid Roshkovan1

  • 1Department of Radiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Insights

Standardizing imaging techniques for malignant pleural mesothelioma (MPM) improves disease assessment. This consensus provides harmonized practices for multimodality imaging in MPM diagnosis and management.

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Malignant pleural mesothelioma (MPM) is a challenging cancer to image accurately.
  • Current imaging lacks standardized approaches for staging and follow-up.

Purpose of the Study:

  • To establish harmonized, standard practices for multimodality imaging of MPM.
  • To improve the quality and reproducibility of imaging for MPM patient care, clinical trials, and research.

Main Methods:

  • Consensus statement developed by an international panel of experts from the International Mesothelioma Interest Group.
  • Review and harmonization of technical approaches for routine multimodality imaging of MPM.

Main Results:

  • Agreement on standard practices for radiography, computed tomography (CT), 18F-2-deoxy-D-glucose positron emission tomography (FDG-PET), and magnetic resonance imaging (MRI).
  • Discussion of modality-specific technical considerations and future research directions.

Conclusions:

  • Harmonized imaging practices are crucial for accurate MPM assessment.
  • Standardized multimodality imaging will enhance patient care, clinical trials, and research in MPM.

Related Concept Videos

Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
275
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
140
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
188
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
390
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
338
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
249