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Neuronal structures controlling locomotor behavior during active and inactive motor states
Hiroshi Nishimaru1, Jumpei Matsumoto1, Tsuyoshi Setogawa1
1System Emotional Science, Faculty of Medicine, University of Toyama, Toyama 930-0194, Japan; Graduate school of Innovative Life Science, University of Toyama, Toyama 930-0194, Japan; Research Center for Idling Brain Science (RCIBS), University of Toyama, Toyama 930-0194, Japan.
Neuroscience Research
|December 22, 2022
Summary
This review explores the brain
Area of Science:
- Neuroscience
- Motor Control
- Animal Behavior
Background:
- Animal behavior alternates between active (movement) and inactive (stationary) states.
- Motor control circuits, from the spinal cord to the cortex, regulate these state transitions.
- Locomotion generation is a key focus in motor control research.
Approach:
- Reviews recent discoveries in rodent models using advanced experimental techniques.
- Focuses on neuronal mechanisms in the brainstem, basal ganglia, and prefrontal cortex.
- Integrates findings with studies on motor control during sleep and cortical state modulation.
Key Points:
- Identifies key brain regions (brainstem, basal ganglia, prefrontal cortex) involved in locomotion control.
- Highlights the role of neuronal circuits in initiating and terminating movement.
- Discusses the interplay between motor control, sleep, and cortical states.
Conclusions:
- The brain utilizes a complex, structured network to manage transitions between active and inactive motor states.
- Recent research has significantly advanced our understanding of the neural basis of locomotion control.
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